Lijuan Gu Selected Research

N-methylisoindigotin

1/2021	Meisoindigo inhibits cellular proliferation via down-regulation of the PI3K/Akt pathway and induces cellular apoptosis in glioblastoma U87 cells.
1/2019	Meisoindigo Protects Against Focal Cerebral Ischemia-Reperfusion Injury by Inhibiting NLRP3 Inflammasome Activation and Regulating Microglia/Macrophage Polarization via TLR4/NF-κB Signaling Pathway.

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Lijuan Gu Research Topics

Disease

13	Neoplasms (Cancer) 10/2022 - 12/2015
11	Stroke (Strokes) 10/2020 - 07/2012
9	Brain Ischemia (Cerebral Ischemia) 01/2022 - 01/2016
9	Inflammation (Inflammations) 01/2022 - 01/2013
7	Ischemic Stroke 01/2022 - 01/2019
6	Reperfusion Injury 01/2022 - 01/2016
4	Carcinogenesis 01/2022 - 01/2019
4	Infarction (Infarctions) 01/2019 - 07/2012
4	Brain Injuries (Brain Injury) 01/2019 - 01/2016
3	Middle Cerebral Artery Infarction (Middle Cerebral Artery Syndrome) 01/2021 - 05/2016
2	Glioma (Gliomas) 10/2022 - 01/2017
2	Brain Edema (Cerebral Edema) 05/2021 - 01/2019
2	Neuroinflammatory Diseases 01/2021 - 01/2016
2	Glioblastoma (Glioblastoma Multiforme) 01/2021 - 01/2017
2	Neoplasm Metastasis (Metastasis) 01/2020 - 01/2019
2	Pathologic Processes 01/2020 - 12/2015
1	Lung Injury 01/2022
1	Hypoxia (Hypoxemia) 01/2022
1	Porcine Reproductive and Respiratory Syndrome (PRRS) 05/2021
1	Microsatellite Instability 01/2021
1	Hepatocellular Carcinoma (Hepatoma) 01/2021
1	Edema (Dropsy) 10/2020
1	Brain Infarction 10/2020
1	Brain Death (Brain Dead) 01/2020
1	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 01/2019
1	Brain Hypoxia-Ischemia (Hypoxia Ischemia, Brain) 01/2019
1	Lung Neoplasms (Lung Cancer) 01/2019
1	Cardiovascular Diseases (Cardiovascular Disease) 07/2017
1	Nervous System Diseases (Neurological Disorders) 01/2017
1	Ischemia 05/2016
1	Adrenocortical Carcinoma 12/2015
1	Adrenocortical Adenoma (Disease, Conn's) 12/2015
1	Pheochromocytoma 12/2015

Drug/Important Bio-Agent (IBA)

10	Proteins (Proteins, Gene)FDA Link 01/2022 - 01/2013
5	InflammasomesIBA 01/2022 - 01/2016
4	Pharmaceutical PreparationsIBA 10/2022 - 04/2014
3	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2022 - 01/2017
3	Biomarkers (Surrogate Marker)IBA 01/2022 - 01/2021
3	T-Cell Antigen Receptors (T-Cell Receptor)IBA 01/2022 - 01/2017
3	Messenger RNA (mRNA)IBA 01/2021 - 12/2015
3	HMGB1 Protein (HMG1)IBA 01/2019 - 01/2013
2	ChemokinesIBA 01/2022 - 01/2021
2	Immune Checkpoint InhibitorsIBA 01/2022 - 01/2017
2	CytokinesIBA 05/2021 - 01/2021
2	EnzymesIBA 01/2021 - 01/2019
2	Neuroprotective AgentsIBA 01/2021 - 10/2020
2	N-methylisoindigotinIBA 01/2021 - 01/2019
2	Oxygen (Dioxygen)IBA 01/2021 - 01/2019
2	Glucose (Dextrose)FDA LinkGeneric 01/2021 - 07/2017
2	Ubiquitin-Specific ProteasesIBA 01/2019 - 12/2015
1	Antineoplastic Agents (Antineoplastics)IBA 10/2022
1	Collagen Type V (Type V Collagen)IBA 01/2022
1	CollagenIBA 01/2022
1	Cyclin-Dependent Kinases (cdk Proteins)IBA 01/2022
1	Pattern Recognition ReceptorsIBA 05/2021
1	Mitogen-Activated Protein KinasesIBA 05/2021
1	NF-kappa B (NF-kB)IBA 05/2021
1	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 01/2021
1	N- (1,2,3,5,6,7- hexahydro- S- indacen- 4- ylcarbamoyl)- 4- (2- hydroxy- 2- propanyl)- 2- furansulfonamideIBA 01/2021
1	Complement System Proteins (Complement)IBA 01/2021
1	IgE Receptors (Fc epsilon RI)IBA 01/2021
1	Janus KinasesIBA 01/2021
1	tanshinone II A sodium sulfonateIBA 10/2020
1	3-methyladenineIBA 10/2020
1	Hydroxyl RadicalIBA 01/2020
1	Ribonucleases (Ribonuclease)IBA 01/2020
1	ribonuclease T(2)IBA 01/2020
1	TRPC6 Cation ChannelIBA 01/2020
1	Superoxides (Superoxide)IBA 01/2020
1	Amino Acids FDA Link 01/2020
1	Nitric Oxide (Nitrogen Monoxide)FDA Link 01/2020
1	Free RadicalsIBA 01/2020
1	DNA (Deoxyribonucleic Acid)IBA 01/2019
1	Matrix Metalloproteinases (MMPs)IBA 01/2019
1	Toll-Like Receptors (Toll-Like Receptor)IBA 01/2019
1	Receptor for Advanced Glycation End ProductsIBA 01/2019
1	ArginaseIBA 01/2018
1	LipidsIBA 07/2017
1	SmokeIBA 07/2017
1	Cancer VaccinesIBA 01/2017
1	AntigensIBA 01/2017
1	Chimeric Antigen ReceptorsIBA 01/2017
1	Isoflurane FDA LinkGeneric 05/2016
1	phospholipid emulsion soybean oil (Intralipid)IBA 05/2016
1	Proto-Oncogene Proteins c-akt (Protein Kinase B)IBA 05/2016
1	Peroxidase (Myeloperoxidase)IBA 01/2016
1	Probenecid (Benemid)FDA LinkGeneric 01/2016
1	Glycyrrhizic Acid (Glycyrrhizin)IBA 01/2016
1	Interleukin-10 (Interleukin 10)IBA 01/2016
1	Interleukin-4 (Interleukin 4)IBA 01/2016
1	InterferonsIBA 01/2016
1	Androgen Receptors (Androgen Receptor)IBA 12/2015
1	Deubiquitinating EnzymesIBA 12/2015

Therapy/Procedure

9	Therapeutics 01/2022 - 04/2014
2	Sutures (Suture) 02/2013 - 07/2012
1	Photothermal Therapy 10/2022
1	Precision Medicine 10/2022
1	Drug Therapy (Chemotherapy) 01/2022
1	Kidney Transplantation 11/2018
1	Immunotherapy 01/2017